Utility of Polymerase Chain Reaction Versus Serology-Based Testing in Immunocompromised Patients With <i>Bartonella henselae</i> Infection-Reference-Cited by-同舟云学术

Utility of Polymerase Chain Reaction Versus Serology-Based Testing in Immunocompromised Patients With Bartonella henselae Infection

Published:2023-03-18 Issue:6 Volume:10 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Kumar Ankit¹,Abdulqader Mohammed¹,McBride Darrell A²

Affiliation:

1. Internal Medicine, Geisinger Medical Center , Danville, Pennsylvania , USA

2. Infectious Diseases, Geisinger Medical Center , Danville, Pennsylvania , USA

Abstract

Abstract Bartonella henselae serologies can be nondiagnostic in immunocompromised individuals due to impaired humoral immunity. Blood polymerase chain reaction (PCR) is more useful diagnostically in immunosuppressed persons. We discuss 3 cases: 2 solid organ transplant (SOT) recipients and 1 person with human immunodeficiency virus (HIV) with positive blood PCR despite negative serology.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofad130/49556307/ofad130.pdf

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