Utility of a Viral Vesicular Panel Multiplex Polymerase Chain Reaction Assay for the Diagnosis of Monkeypox, Herpes Simplex, and Varicella Zoster Viruses

Author:

Wilber Eli1ORCID,Rebolledo Paulina A123,Kasinathan Vyjayanti4,Merritt Stephanie5,Titanji Boghuma K1,Aldred Bruce1,Kandiah Sheetal1,Ray Susan M123,Sheth Anandi N13,Colasanti Jonathan A123,Wang Yun F45

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine , Atlanta, Georgia , USA

2. Hubert Department of Global Health, Rollins School of Public Health, Emory University , Atlanta, Georgia , USA

3. Grady Healthcare System , Atlanta, Georgia , USA

4. Department of Pathology and Laboratory Medicine, Emory University School of Medicine , Atlanta, Georgia , USA

5. Grady Memorial Hospital, Clinical Laboratory , Atlanta, Georgia , USA

Abstract

AbstractMpox (monkeypox) represents a diagnostic challenge due to varied clinical presentations and multiple mimics. A commercially available multiplex polymerase chain reaction panel accurately detects mpox virus as well as common mimics (herpes simplex virus, varicella zoster virus) in clinical specimens and could be used in routine clinical, surveillance, and outbreak settings.

Funder

Center for AIDS Research

Emory University

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

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