Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort-Reference-Cited by-同舟云学术

Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort

Published:2021-07-01 Issue:7 Volume:8 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Koay Wei Li A¹²^ORCID,Dirajlal-Fargo Sahera³⁴⁵,Levy Matthew E⁶⁷,Kulie Paige⁶,Monroe Anne⁶,Castel Amanda D⁶,Rakhmanina Natella Y¹²⁸,D’Angelo Lawrence,Rakhmanina Natella,Kharfen Michael,Serlin Michael,Kumar Princy,Bamdad Aria,Bezabeh Tsedenia,Burrows Pamela Katzen,Reamer Susan,Sapozhnikova Alla,Temprosa Marinella,Younes Naji,Byrne Morgan,Castel Amanda,Greenberg Alan,Jaurretche Maria,Levy Matthew,Monroe Anne,Peterson James,Happ Lindsey Powers,Wilbourn Brittany,Ma Yan,Akselrod Hana,Wilcox Ronald,Rana Sohail,Horberg Michael,Fernandez Ricardo,Hebou Annick,Dieffenbach Carl,Masur Henry,Bordon Jose,Teferi Gebeyehu,Benator Debra,Ruiz Maria Elena,Abbott Stephen,

Affiliation:

1. Department of Infectious Diseases, Children’s National Hospital, Washington, District of Columbia, USA

2. School of Medicine and Health Sciences, George Washington University, Washington, District of Columbia, USA

3. School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA

4. University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA

5. Pediatric Infectious Diseases, Rainbow Babies and Children’s Hospital, Cleveland, Ohio, USA

6. Milken Institute School of Public Health, George Washington University, Washington, District of Columbia, USA

7. Westat, Rockville, Maryland, USA

8. Elizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia, USA

Abstract

Abstract We conducted a retrospective analysis of 38 children and youth with human immunodeficiency virus (aged 0–19 years) in the United States and report an increased rate of change of BMI-for-age z score after initiating integrase strand transfer inhibitors (+0.19 z score units/year [95% confidence interval, .01–.37]; P = .036) for a median follow-up of 527.5 days.

Funder

National Institute of Allergy and Infectious Diseases

National Institutes of Health

National Cancer Institute

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Heart, Lung, and Blood Institute

National Institute on Drug Abuse

National Institute of Mental Health

National Institute on Aging

Fogarty International Center

National Institute of General Medical Sciences

National Institute of Diabetes and Digestive and Kidney Diseases