Poor Sensitivity of Stool Culture Compared to Polymerase Chain Reaction in Surveillance for <i>Vibrio cholerae</i> in Haiti, 2018

Poor Sensitivity of Stool Culture Compared to Polymerase Chain Reaction in Surveillance for Vibrio cholerae in Haiti, 2018–2019

Published:2023-06-01 Issue:6 Volume:10 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Guillaume Yodeline¹,Debela Meti²,Slater Damien¹,Vissieres Kenia³,Ternier Ralph³,Franke Molly F³,Harris Jason B¹,Ivers Louise C¹⁴

Affiliation:

1. Massachusetts General Hospital , Boston, Massachusetts , USA

2. University of Massachusetts Chan Medical School , Worcester, Massachusetts , USA

3. Department of Clinical Programs, Zanmi Lasante , Croix-des-Bouquets , Haiti

4. Department of Global Health and Social Medicine, Harvard Medical School , Boston, Massachusetts , USA

Abstract

Abstract We report on the sensitivity and specificity of stool culture compared to polymerase chain reaction for detecting Vibrio cholerae in Haiti during the waning period of the initial outbreak in 2018–2019. We found that stool culture (with a sensitivity of 33.3% and specificity of 97.4%) may not be sufficiently robust in this context.

Funder

Bill & Melinda Gates Foundation

National Institute of Allergy and Infectious Diseases

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofad301/50517649/ofad301.pdf

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