Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality-Reference-Cited by-同舟云学术

Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality

Published:2021-06-30 Issue:7 Volume:8 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Soria Jaime¹²^ORCID,Chiappe Alfredo³²,Gallardo Jorge³,Zunt Joseph R⁴,Lescano Andres G⁵

Affiliation:

1. Division of Infectious Diseases, University of Kentucky, Lexington, Kentucky, USA

2. Northern Pacific Global Health Research Fellows Training Consortium, University of Washington, Seattle, Washington, USA

3. Department of Infectious Diseases, Hospital Nacional Dos de Mayo, Lima, Peru

4. Departments of Neurology, Global Health, Medicine (Infectious Diseases), and Epidemiology, University of Washington, Seattle, Washington, USA

5. Emerge, Emerging Diseases and Climate Change Research Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru

Abstract

Abstract We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality. The mortality of tuberculous meningitis patients was high and was associated with delay in initiation of treatment, older age, HIV infection, and higher disease severity at admission.

Funder

NIH Research Training

Fogarty International Center

NIH Office of the Director Office of AIDS Research

NIH Office of the Director Office of Research on Women’s Health

National Institute of Mental Health

National Heart, Lung, and Blood Institute

National Institute of General Medical Sciences

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology