Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease-Reference-Cited by-同舟云学术

Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease

Published:2021-05-16 Issue:7 Volume:8 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Shojaei Esfandiar¹^ORCID,Walsh Joanna C²,Sangle Nikhil²,Yan Brian³,Silverman Michael S¹⁴,Hosseini-Moghaddam Seyed M¹⁵^ORCID

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada

2. Department of Pathology and Laboratory Medicine, London Health Sciences Centre, Western University, London, Ontario, Canada

3. Division of Gastroenterology, Department of Medicine, Schulich School of Medicine & Dentistry, London Health Sciences Centre, Western University, London, Ontario, Canada

4. Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada

5. Division of Infectious Diseases, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada

Abstract

Abstract Disseminated histoplasmosis is a life-threatening disease usually seen in immunocompromised patients living in endemic areas. We present an apparently immunocompetent patient with gastrointestinal histoplasmosis who was initially diagnosed with biopsy-proven Crohn’s disease. Following discontinuation of anti-inflammatory drugs and institution of antifungal therapy, his gastrointestinal illness completely improved. Specific fungal staining should be routinely included in histopathologic assessment of tissue specimens diagnosed as Crohn’s disease.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofab249/37940215/ofab249.pdf

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