Human Immunodeficiency Virus Type 1 RNA Genital Tract Shedding After Cryotherapy for Cervical Intraepithelial Neoplasia in Western Kenya

Author:

Orang’o Elkanah Omenge1,Bocage Anne E2ORCID,Liu Tao D3ORCID,Itsura Peter M1,Tonui Philip K1,Muthoka Kapten4,Stephen Kiptoo1,Caliendo Angela M5,Sam Soya S56,Cu-Uvin Susan5

Affiliation:

1. Department of Reproductive Health, Moi University , Eldoret , Kenya

2. Warren Alpert Medical School of Brown University , Providence, Rhode Island , USA

3. Department of Biostatistics, Brown University , Providence, Rhode Island , USA

4. Academic Model Providing Access to Healthcare Partnership , Eldoret , Kenya

5. Division of Infectious Disease, The Warren Alpert Medical School of Brown University , Providence, Rhode Island , USA

6. Division of Infectious Diseases, Miriam Hospital , Providence, Rhode Island , USA

Abstract

Abstract This prospective study of 39 women living with human immunodeficiency virus (HIV) on antiretroviral therapy in Western Kenya aimed to quantify genital tract HIV-1 RNA (GT-HIV RNA) shedding before and after cryotherapy for cervical intraepithelial neoplasia. Most GT-HIV RNA shedding was detected precryotherapy, suggesting that cryotherapy was not the primary cause of shedding.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

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