Molecular Characterization of <i>Trypanosoma cruzi</i> Reactivation and Follow-up in a Case Series of People With HIV-Reference-Cited by-同舟云学术

Molecular Characterization of Trypanosoma cruzi Reactivation and Follow-up in a Case Series of People With HIV

Published:2023-07-10 Issue:8 Volume:10 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Fernandez Marisa Liliana¹²^ORCID,Albizu Constanza Lopez¹,Nicita Diego²,Besuschio Susana³,Giomi Cinthia²,Biondi María Laura²,Leguizamón María Susana⁴⁵,Garcia Julian²,Corti Marcelo²,Schijman Alejandro³⁵,Burgos Juan Miguel⁴⁵

Affiliation:

1. Instituto Nacional de Parasitología Dr M. Fatala Chabén, Administración Nacional de Laboratorios e Institutos de Salud Dr C. Malbrán, Ministerio de Salud , Buenos Aires , Argentina

2. Departamento de Enfermedades Infecciosas, Hospital de Infecciosas Francisco Javier Muñiz , Buenos Aires , Argentina

3. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular “Dr Hector Torres,” Consejo Nacional de Investigaciones Científicas y Técnicas , Buenos Aires , Argentina

4. IIBIO, Universidad Nacional de San Martín , Buenos Aires , Argentina

5. Consejo Nacional de Investigaciones Científicas y Técnicas , CONICET, Buenos Aires , Argentina

Abstract

Abstract We characterize Trypanosoma cruzi infections from blood and cerebrospinal fluid samples in a case series of people with human immunodeficiency virus and Chagas disease. We identify different infecting T. cruzi populations, highlighting the usefulness of real-time polymerase chain reaction for Chagas disease reactivation diagnosis and evaluation of treatment response.

Funder

Administración Nacional de Laboratorios e Institutos de Salud

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofad357/50850479/ofad357.pdf

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