In Utero Exposure to Maternal SARS-CoV-2 Infection Is Associated With Higher Left Ventricular Mass in Toddlers-Reference-Cited by-同舟云学术

In Utero Exposure to Maternal SARS-CoV-2 Infection Is Associated With Higher Left Ventricular Mass in Toddlers

Published:2024-05-31 Issue:6 Volume:11 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Ockene Mollie W¹^ORCID,Balaguru Duraisamy²^ORCID,Ma Ingrid L¹,Russo Samuel C¹,Arpante Allison K¹,Clifford Alexandra¹,Jasset Olyvia J³,Kim Joon H³,Toribio Mabel¹^ORCID,Stanley Takara L¹^ORCID,Shook Lydia L³⁴,Edlow Andrea G³⁴,Fourman Lindsay T¹^ORCID

Affiliation:

1. Metabolism Unit, Massachusetts General Hospital , Boston, Massachusetts , USA

2. Pediatric Cardiology, Massachusetts General Hospital , Boston, Massachusetts , USA

3. Vincent Center for Reproductive Biology, Massachusetts General Hospital , Boston, Massachusetts , USA

4. Department of Obstetrics and Gynecology, Maternal-Fetal Medicine Division, Massachusetts General Hospital and Harvard Medical School , Boston, Massachusetts , USA

Abstract

Abstract The intrauterine environment plays a critical role in shaping chronic disease risk over the life course. We prospectively evaluated cardiometabolic outcomes in toddlers born to mothers with versus without prenatal severe acute respiratory syndrome coronavirus 2 infection. Children with in utero severe acute respiratory syndrome coronavirus 2 exposure had higher left ventricular mass in association with altered maternal immunologic indices.

Funder

National Institutes of Health

Harvard Nutrition Obesity Research Center at Harvard Pilot and Feasibility

Boston Area Diabetes Endocrinology Research Centers Pilot and Feasibility

Harvard Clinical and Translational Science Center

American Heart Association

Harold Amos Medical Research Faculty Development Program

Robert Wood Johnson Foundation

Simons Foundation

Publisher

Oxford University Press (OUP)

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