Extensively Drug-Resistant Typhoid Fever in the United States

Author:

Hughes Michael J1,Birhane Meseret G1,Dorough Layne12,Reynolds Jared L1,Caidi Hayat1,Tagg Kaitlin A13,Snyder Caroline M12,Yu Alexander T4,Altman Shana M5,Boyle Michelle M6,Thomas Deepam7,Robbins Amy E8,Waechter HaeNa A9,Cody Irina10,Mintz Eric D1,Gutelius Bruce1,Langley Gayle1,Francois Watkins Louise K1

Affiliation:

1. Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

2. Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA

3. WDS, Inc., Decatur, Georgia, USA

4. Infectious Diseases Branch, Division of Communicable Disease Control, California Department of Public Health, Richmond, California, USA

5. Illinois Department of Public Health, Springfield, Illinois, USA

6. Maryland Department of Health, Baltimore, Maryland, USA

7. New Jersey Department of Health, Trenton, New Jersey, USA

8. New York State Department of Health, Albany, New York, USA

9. New York City Department of Health and Mental Hygiene, New York, New York, USA

10. Emerging and Acute Infectious Disease Unit, Texas Department of State Health Services, Austin, Texas, USA

Abstract

Abstract Cases of extensively drug-resistant (XDR) typhoid fever have been reported in the United States among patients who did not travel internationally. Clinicians should consider if and where the patient traveled when selecting empiric treatment for typhoid fever. XDR typhoid fever should be treated with a carbapenem, azithromycin, or both.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Reference26 articles.

1. Complications and mortality of typhoid fever: a global systematic review and meta-analysis.;Marchello;J Infect,2020

2. Systematic review of the global epidemiology, clinical and laboratory profile of enteric fever.;Azmatullah;J Glob Health,2015

3. Typhoid: clinical analysis of three hundred and sixty cases.;Stuart;ArchIntern Med,1946

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