R-CHOP Chemotherapy for Disseminated Mycobacterium avium Complex Disease due to Anti-Interferon-Gamma Autoantibodies: A Case Report-Reference-Cited by-同舟云学术

R-CHOP Chemotherapy for Disseminated Mycobacterium avium Complex Disease due to Anti-Interferon-Gamma Autoantibodies: A Case Report

Published:2021-04-10 Issue:6 Volume:8 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Uno Shunsuke¹^ORCID,Uehara Eisuke²,Kimura Toshiki³,Sakagami Takuro³^ORCID,Namkoong Ho⁴^ORCID,Uchida Sho¹^ORCID,Uwamino Yoshifumi⁵^ORCID,Hasegawa Naoki¹^ORCID

Affiliation:

1. Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan

2. Department of Hematology, Sainokuni Higashiomiya Medical Center, Saitama, Japan

3. Department of Respiratory Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

4. Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

5. Department of Laboratory Medicine, Keio University School of Medicine, Tokyo, Japan

Abstract

Abstract A 77-year-old Japanese man with disseminated Mycobacterium avium complex (MAC) disease due to anti-interferon-gamma autoantibodies received rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP) chemotherapy because of non-Hodgkin lymphoma complication. The hepatobiliary nodules due to MAC resolved with R-CHOP and multidrug antimycobacterial treatment. R-CHOP could serve as an alternative adjunctive therapy for patients with anti-interferon-gamma autoantibodies.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofab181/37016931/ofab181.pdf

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