Evaluation of 2 Lateral Flow Rapid Tests in the Diagnosis of Chagas Disease in the Washington Metropolitan Area

Author:

Castro-Sesquen Yagahira E1ORCID,Saldaña Antonella1,Patino Nava Dhayanna1,Paulette Evans Diana1,Bayangos Tabitha1,DeToy Kelly1,Trevino Alexia1,Marcus Rachel2,Bern Caryn3,Gilman Robert H1,Talaat Kawsar R1,Avila Carol,Camacho Fabiola,Herrera Sdenka,Jimenez Andres,Lozano Veronika,Malaga Edith,Merida Mariel,Morales Carolina,Solis Rodrigo,Sotomayor Fiorella,Tung Alisha,Spector Anna,Verastegui Manuela,Yang Younghee,Zapata Fatima,

Affiliation:

1. Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

2. MedStar Washington Hospital Center, Washington, DC, USA

3. Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, California, USA

Abstract

Abstract We compared the accuracy of the Stat-Pak and Chagas Detect Plus with a latent class analysis. Sensitivity values of 89.7% and 91.9% and specificities of 97.1% and 80.3%, respectively, were seen in the serodiagnosis of Chagas disease in Hispanic immigrants, revealing the limitations of these tests in diverse populations.

Funder

Fondo Nacional de Desarrollo Científico, Tecnológico y de Innovación Tecnológica

National Institutes of Health

InBios International, Inc

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Reference13 articles.

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2. Use of a latent class analysis in the diagnosis of chronic Chagas disease in the Washington Metropolitan area;Castro-Sesquen;Clin Infect Dis

3. Over six thousand Trypanosoma cruzi strains classified into discrete typing units (DTUs): attempt at an inventory;Brenière;PLoS Negl Trop Dis,2016

4. Congenital Trypanosoma cruzi transmission in Santa Cruz, Bolivia;Bern;Clin Infect Dis,2009

5. Rapid diagnostic tests duo as alternative to conventional serological assays for conclusive Chagas disease diagnosis;Egüez;PLoS Negl Trop Dis,2017

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