Transient Parvovirus B19 DNAemia After Kidney Transplantation: A 2-Sided Story-Reference-Cited by-同舟云学术

Transient Parvovirus B19 DNAemia After Kidney Transplantation: A 2-Sided Story

Published:2023-02-14 Issue:3 Volume:10 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Russcher Anne¹,Molenaar-de Backer Marijke²,de Brouwer Caroline¹,Dijkstra Kyra³,Kers Jesper³,de Vries Aiko⁴^ORCID,Zaaijer Hans²,Vossen Ann¹,Kroes Aloysius¹

Affiliation:

1. Department of Medical Microbiology, Leiden University Medical Center , Leiden , The Netherlands

2. Donor Medicine Research, Department of Blood-borne Infections, Sanquin Blood Supply Foundation , Amsterdam , The Netherlands

3. Department of Pathology and Leiden Transplant Center, Leiden University Medical Center , Leiden , The Netherlands

4. Department of Nephrology and Leiden Transplant Center, Leiden University Medical Center , Leiden , The Netherlands

Abstract

AbstractParvovirus B19 (B19V) DNAemia appears to be a relatively common finding after kidney transplantation. However, not all DNAemia signifies active infection with replicating virus. This study screened 134 patients posttransplantation for B19V DNAemia and identified 2 cases in which viral DNA was present after transplantation, with the donor kidney as probable source of the DNA. In both cases intact viral particles could not be detected using an endonuclease method, indicating the presence of noninfectious DNA remnants.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofad079/49179813/ofad079.pdf

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