Combination Antifungal Therapy for Invasive Mucormycosis in Immunocompromised Hosts: A Single-Center Experience

Author:

Lu Brian1ORCID,Ha David23,Shen Sa4,Ferguson Toll Jessica3,Kim Ailin1,Kim Sarah1,Mui Emily23,Deresinski Stan23,Holubar Marisa23ORCID,Alegria William23

Affiliation:

1. Department of Pharmacy, Stanford Health Care , Stanford, California , USA

2. Department of Quality, Stanford Health Care , Stanford, California , USA

3. Division of Infectious Diseases and Geographic Medicine, School of Medicine, Stanford University , Stanford, California , USA

4. Quantitative Sciences Unit, School of Medicine, Stanford University , Stanford, California , USA

Abstract

Abstract Combination antifungal therapy for invasive mucormycosis remains controversial and is inconsistently defined in prior studies. In a cohort of patients with immunocompromised status and invasive mucormycosis, we found no difference in 6-week mortality with up-front or salvage combination therapy as compared with monotherapy.

Publisher

Oxford University Press (OUP)

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