Case Report: Overwhelming Babesia Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone-Reference-Cited by-同舟云学术

Case Report: Overwhelming Babesia Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone

Published:2020-09-23 Issue:10 Volume:7 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Li Yijia¹²^ORCID,Stanley Susan¹²,Villalba Julian A³,Nelson Sandra¹,Gelfand Jeffrey¹

Affiliation:

1. Infectious Diseases Unit, Massachusetts General Hospital, Boston, Massachusetts, USA

2. Division of Infectious Diseases Brigham and Women’s Hospital, Boston, Massachusetts, USA

3. Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA

Abstract

AbstractBabesiosis with high-grade parasitemia is life-threatening, especially in asplenic hosts. We report an asplenic patient with parasitemia >50% who was successfully treated with prompt red blood cell apheresis and triple therapy with clindamycin + azithromycin + atovaquone. This regimen may be an alternative to poorly tolerated clindamycin + quinine in severe cases.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofaa448/33783694/ofaa448.pdf

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