Diagnostic Yield of Urine Xpert MTB/RIF Ultra in Adults With Suspected Extrapulmonary Tuberculosis

Author:

Ndege Robert1234ORCID,Rohacek Martin1234,Bani Farida14,Ngome Omary1,Okuma James23,Sasamalo Mohamed1,Mnzava Dorcas1,Reither Klaus23,Vanobberghen Fiona23,Hella Jerry1,Paris Daniel H23,Weisser Maja1235

Affiliation:

1. Biomedical Research and Clinical Trials Department, Ifakara Health Institute , Ifakara , Tanzania

2. Department of Medicine, Swiss Tropical and Public Health Institute , Allschwil , Switzerland

3. University of Basel , Basel , Switzerland

4. St Francis Regional Referral Hospital Internal Medicine Department, , Ifakara , Tanzania

5. Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Basel , Basel , Switzerland

Abstract

Abstract We assessed the diagnostic yield of urine GeneXpert MTB/RIF Ultra and factors associated with a positive test among adult patients suspected to have extrapulmonary tuberculosis. Urine Ultra was positive in 14% of participants with definite or probable tuberculosis. Hospitalization, disseminated tuberculosis, and human immunodeficiency virus infection were associated with a positive result.

Funder

Rudolf Geigy Foundation

Gottfried and Julia Bangerter-Rhyner Foundation, Basel

Publisher

Oxford University Press (OUP)

Reference14 articles.

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