A Case of Sustained Viral Shedding of Mpox With Ocular Involvement Resulting in Vision Loss-Reference-Cited by-同舟云学术

A Case of Sustained Viral Shedding of Mpox With Ocular Involvement Resulting in Vision Loss

Published:2023-12-14 Issue:1 Volume:11 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Speiser Lisa J¹^ORCID,Wonnaparhown Alex M²,Blair Janis¹,Shah Ami³,Patel Dharmendra R³,McCullough Ann E⁴,Nicolasora Nelson⁵,Khalsa Ann M⁶,Orenstein Robert¹,Vikram Holenarasipur R¹,Huang Vivian⁷⁸,Seville Maria Teresa¹

Affiliation:

1. Department of Medicine, Division of Infectious Diseases , The Mayo Clinic Arizona, Phoenix, Arizona , USA

2. Department of Medicine, Division of Allergy and Immunology, The Mayo Clinic Arizona , Phoenix, Arizona , USA

3. Department of Ophthalmology, The Mayo Clinic Arizona , Phoenix, Arizona , USA

4. Department of Laboratory Medicine and Pathology, Division of Anatomic Pathology, The Mayo Clinic Arizona , Phoenix, Arizona , USA

5. Department of Medicine, Banner University Medical Center , Phoenix, Arizona , USA

6. Department of Family Medicine, Valleywise Health Medical Center , Phoenix, Arizona , USA

7. Maricopa County Department of Public Health, Division of Epidemiology and Public Health Informatics , Phoenix, Arizona , USA

8. Department of Medical Affairs, Novavax Inc. , Gaithersburg, Maryland , USA

Abstract

Abstract Mpox, caused by infection with Monkeypox virus, usually presents as a mild, self-limited illness in immunocompetent persons that resolves within 2–4 weeks. Serious complications have been reported when mpox lesions involve vulnerable anatomic sites, such as the eye, and in those with substantial immunosuppression. We describe a patient with advanced human immunodeficiency virus infection and sustained viral shedding of mpox with ocular involvement, which resulted in vision loss.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofad632/54450588/ofad632.pdf

Reference32 articles.

1. The detection of monkeypox in humans in the Western Hemisphere;Reed;N Engl J Med,2004

2. Monkeypox outbreak—nine states, May 2022;Minhaj;MMWR Morb Mortal Wkly Rep,2022

3. Severe monkeypox in hospitalized patients—United States, August 10–October 10, 2022;Miller;MMWR Morb Mortal Wkly Rep,2022