An overview of key online resources for human genomics: a powerful and open toolbox for in silico research

Author:

Forero Diego A1ORCID,Bonilla Diego A234,González-Giraldo Yeimy5,Patrinos George P6789101112

Affiliation:

1. School of Health and Sport Sciences, Fundación Universitaria del Área Andina , Bogotá , Colombia

2. Research Division, Dynamical Business & Science Society – DBSS International SAS , Bogotá , Colombia

3. Hologenomiks Research Group , Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, , Leioa , Spain

4. University of the Basque Country (UPV/EHU) , Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, , Leioa , Spain

5. Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana , Bogotá , Colombia

6. Laboratory of Pharmacogenomics and Individualized Therapy , Department of Pharmacy, School of Health Science, , Patras , Greece

7. University of Patras , Department of Pharmacy, School of Health Science, , Patras , Greece

8. Clinical Bioinformatics Unit , Department of Pathology, School of Medicine and Health Sciences, , Rotterdam , The Netherlands

9. Erasmus University Medical Center , Department of Pathology, School of Medicine and Health Sciences, , Rotterdam , The Netherlands

10. Department of Genetics and Genomics , College of Medicine and Health Sciences, , Abu Dhabi , United Arab Emirates

11. United Arab Emirates University, Al-AIn , College of Medicine and Health Sciences, , Abu Dhabi , United Arab Emirates

12. Zayed Center for Health Sciences, United Arab Emirates University, Al-AIn , Abu Dhabi , United Arab Emirates

Abstract

Abstract Recent advances in high-throughput molecular methods have led to an extraordinary volume of genomics data. Simultaneously, the progress in the computational implementation of novel algorithms has facilitated the creation of hundreds of freely available online tools for their advanced analyses. However, a general overview of the most commonly used tools for the in silico analysis of genomics data is still missing. In the current article, we present an overview of commonly used online resources for genomics research, including over 50 tools. This selection will be helpful for scientists with basic or intermediate skills in the in silico analyses of genomics data, such as researchers and students from wet labs seeking to strengthen their computational competencies. In addition, we discuss current needs and future perspectives within this field.

Funder

Minciencias and Areandina-DNI

UNU-BIOLAC

European Commission

International Brain Research Organization

Department of Neuroscience and Regenerative Medicine

Medical College of Georgia

Augusta University

Sistema General de Regalías

Publisher

Oxford University Press (OUP)

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