Seroprevalence of Coxiella burnetii (Q fever) Exposure in Humans on Reunion Island-Reference-Cited by-同舟云学术

Seroprevalence of Coxiella burnetii (Q fever) Exposure in Humans on Reunion Island

Published:2019-05-15 Issue:7 Volume:6 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Jaubert Julien¹,Naze Florence¹,Camuset Guillaume²,Larrieu Sophie³,Pascalis Hervé⁴,Guernier Vanina⁵,Naty Nadège⁶,Bertolotti Antoine²⁶,Manaquin Rodolphe²,Mboussou Yoan¹,Atiana Laura¹,Picot Sandrine¹,Filleul Laurent³,Tortosa Pablo⁴,Cardinale Eric⁷⁸,Gérardin Patrick⁴⁶^ORCID

Affiliation:

1. Laboratoire de Bactériologie, Virologie et Parasitologie, Centre Hospitalier Universitaire (CHU) de la Réunion, Saint Pierre, Reunion, France

2. Service des Maladies Infectieuses, CHU de la Réunion, Saint Pierre, Reunion, France

3. Cellule d’Intervention Régionale et d’Epidémiologie, Océan Indien, Santé Publique France, French National Public Health Agency, Saint Denis, Reunion, France

4. UM 134 PIMIT Processus Infectieux en Milieu Insulaire Tropical, Université de La Réunion, INSERM 1187, CNRS 9192, IRD 249, CYROI, Sainte Clotilde, Reunion, France

5. Geelong Centre for Emerging Infectious Diseases, Deakin University, Geelong, Victoria, Australia

6. INSERM Centre d’Investigation Clinique 1410 Epidémiologie Clinique, CHU Réunion, Saint Pierre, Reunion, France

7. UMR ASTRE, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD) CYROI platform, Sainte Clotilde, Reunion, France

8. UMR 1309 ASTRE, Institut National de Recherche Agronomique (INRA), Montpellier, France

Abstract

Abstract After the documentation of sporadic cases of Q fever endocarditis, we conducted a serosurvey to assess Coxiella burnetii exposure on Reunion Island. Two hundred forty-one stored frozen human sera were analyzed using an immunofluorescence assay. The weighted seroprevalence of Q fever was of 6.81% (95% confidence interval, 4.02%–9.59%). Despite the absence of infection in youths <20 years of age, exposure was not driven by age or by gender. There was a spatial disparity in exposure across the island, with higher prevalence being reported in regions where ruminant farms are present. The seroprevalence pattern suggests that Q fever is endemic on Reunion Island.

Funder

Contrat Programme Etat/Region and European Regional Development Fund

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofz227/28650913/ofz227.pdf

Reference16 articles.

1. From Q fever to Coxiella burnetii infection: a paradigm change;Eldin;Clin Microbiol Rev,2017

2. Q fever in French Guiana: tip of the iceberg or epidemiological exception?;Epelboin;PLoS Negl Trop Dis,2016

3. Epidemic of Q fever in Tul’ear (Republic of Madagascar);Guiot;Bull Soc Pathol Exot Filiales,1964