Clostridioides difficile Enteritis in Patients Following Total Colectomy—a Rare but Genuine Clinical Entity-Reference-Cited by-同舟云学术

Clostridioides difficile Enteritis in Patients Following Total Colectomy—a Rare but Genuine Clinical Entity

Published:2019-10-31 Issue:11 Volume:6 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Ulrich Robert J¹^ORCID,Bott Jonathan¹²,Imlay Hannah¹,Lopez Kerri³,Cinti Sandro¹²,Rao Krishna¹²⁴

Affiliation:

1. Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA

2. Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, Michigan, USA

3. University of Michigan Medical School, Ann Arbor, Michigan, USA

4. Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA

Abstract

Clostridioides difficile enteritis (CDE) after colectomy is an understudied infectious syndrome. We reviewed 20 years of post-colectomy data and found CDE in 44/855 (5.1%) patients, usually within one year of surgery. Risk factors include acid suppression, inflammatory bowel disease, and antibiotics with enteral feeds. Clostridioides difficile enteritis often presents with severe disease requiring hospitalization.

Funder

Claude D. Pepper Older Americans Independence Center

Michigan Institute for Clinical and Health Research

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/6/11/ofz409/30338715/ofz409.pdf

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