When Ventricular Cerebrospinal Fluid Assessment Misleads: Basal Meningitis and the Importance of Lumbar Puncture Sampling-Reference-Cited by-同舟云学术

When Ventricular Cerebrospinal Fluid Assessment Misleads: Basal Meningitis and the Importance of Lumbar Puncture Sampling

Published:2019-07-01 Issue:7 Volume:6 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Khan Sadid F¹,Macauley Thornton¹,Tong Steven Y C¹²³,Xie Ouli¹,Hughes Carly¹,Hall Nicholas D P⁴⁵,Mahanty Siddhartha¹²,Jennens Ian¹²,Street Alan C¹²

Affiliation:

1. Victorian Infectious Disease Service, The Royal Melbourne Hospital, Melbourne, Victoria, Australia

2. Doherty Department University of Melbourne, Peter Doherty Institute for Infection and Immunity, Victoria, Australia

3. Menzies School of Health Research, Darwin, Northern Territory, Australia

4. Department of Neurosurgery, The Royal Melbourne Hospital, Melbourne, Victoria, Australia

5. Department of Surgery, University of Melbourne, Melbourne, Victoria, Australia

Abstract

Abstract The diagnosis of central nervous system (CNS) infection relies upon analysis of cerebrospinal fluid (CSF). We present 4 cases of CNS infections associated with basal meningitis and hydrocephalus with normal ventricular CSF but grossly abnormal lumbar CSF. We discuss CSF ventricular–lumbar composition gradients and putative pathophysiological mechanisms and highlight clinical clues for clinicians.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofz324/28917715/ofz324.pdf

Reference12 articles.

1. Does lumbar cerebrospinal fluid reflect ventricular cerebrospinal fluid? A prospective study in patients with external ventricular drainage;Sommer;Eur Neurol,2002

2. Clinical utility of biochemical analysis of cerebrospinal fluid;Watson;Clin Chem,1995

3. Lumbar and ventricular CSF protein, leukocytes, and lactate in suspected bacterial CNS infections;Gerber;Neurology,1998

4. Normal ventricular-CSF may confound the diagnosis of tuberculous meningitis hydrocephalus;Alfayate-Miguélez;Neurocirugia (Astur),2011

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A teenage girl with altered mental status and paraparesis;Journal of Clinical Tuberculosis and Other Mycobacterial Diseases;2024-05

2. Recommendations for reproducibility of cerebrospinal fluid extracellular vesicle studies;Journal of Extracellular Vesicles;2023-12-29

3. Cerebrospinal Fluid–Basic Concepts Review;Biomedicines;2023-05-17

4. Spatial and temporal variation of routine parameters: pitfalls in the cerebrospinal fluid analysis in central nervous system infections;Journal of Neuroinflammation;2022-07-06

5. Cerebrospinal fluid osmolality cannot predict development or surgical outcome of idiopathic normal pressure hydrocephalus;Fluids and Barriers of the CNS;2022-06-27