An integrated abundance model for estimating county-level prevalence of opioid misuse in Ohio

Author:

Hepler Staci A1,Kline David M2ORCID,Bonny Andrea3,McKnight Erin3,Waller Lance A4ORCID

Affiliation:

1. Department of Statistical Sciences, Wake Forest University , Winston-Salem , USA

2. Department of Biostatistics and Data Science, Wake Forest University School of Medicine , Winston-Salem , USA

3. Division of Adolescent Medicine, Nationwide Children’s Hospital, Department of Pediatrics, The Ohio State University , Columbus , USA

4. Department of Biostatistics and Bioinformatics, Emory University , Atlanta , USA

Abstract

AbstractOpioid misuse is a national epidemic and a significant drug-related threat to the United States. While the scale of the problem is undeniable, estimates of the local prevalence of opioid misuse are lacking, despite their importance to policy-making and resource allocation. This is due, in part, to the challenge of directly measuring opioid misuse at a local level. In this paper, we develop a Bayesian hierarchical spatio-temporal abundance model that integrates indirect county-level data on opioid-related outcomes with state-level survey estimates on prevalence of opioid misuse to estimate the latent county-level prevalence and counts of people who misuse opioids. A simulation study shows that our integrated model accurately recovers the latent counts and prevalence. We apply our model to county-level surveillance data on opioid overdose deaths and treatment admissions from the state of Ohio. Our proposed framework can be applied to other applications of small area estimation for hard to reach populations, which is a common occurrence with many health conditions such as those related to illicit behaviours.

Publisher

Oxford University Press (OUP)

Subject

Statistics, Probability and Uncertainty,Economics and Econometrics,Social Sciences (miscellaneous),Statistics and Probability

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