‘Cut medicine for me’: addressing suboptimal dosing of antimicrobials as a critical issue to combat AMR in Nigeria

Author:

Egwu Kenneth Chukwuebuka1ORCID,Abdulkarim Maryam2,Eze Shadrach Chinecherem3,Mbamalu Oluchi45ORCID

Affiliation:

1. Department of Pharmacy, University of Nigeria Teaching Hospital , Ituku-Ozalla, Enugu State , Nigeria

2. Department of Molecular Biology and Biotechnology, University of Sheffield , Sheffield , UK

3. Department of Pharmacy, Federal Teaching Hospital , Ido-Ekiti, Ekiti State , Nigeria

4. Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University , Cape Town , South Africa

5. Global Surgery Division, Faculty of Health Sciences, University of Cape Town , Cape Town , South Africa

Abstract

Abstract Antimicrobial resistance (AMR) is a critical health challenge in Nigeria as in many other countries in the sub-Saharan region of Africa. Our article describes how the challenges in the regulation and operations of Patent and Proprietary Medicine Vendors (PPMVs) in Nigeria provide a blind spot for the underuse of antimicrobials. This article also sheds light on how patients’ antibiotic use and seeking behaviour facilitate this unwholesome practice. In addition, our article looks at the social determinants of this practice, such as poverty and poor education, and proffers solutions towards solving it. While previous research has investigated the knowledge, perceptions and attitudes of PPMVs towards antimicrobial use and AMR, our article is the first to critically raise concerns about the common practice of antimicrobial underdosing in Nigeria.

Publisher

Oxford University Press (OUP)

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