Exploring barriers to guideline implementation for prescription of surgical antibiotic prophylaxis in Nigeria

Author:

Wood Caroline E.1,Luedtke Susanne1,Musah Anwar1,Bammeke Funmi2,Mutiu Bamidele3,Ojewola Rufus4,Bankole Olufemi5,Ademuyiwa Adesoji Oludotun6,Ekumankama Chibuzo Barbara7,Ogunsola Folasade3,Okonji Patrick3,Kpokiri Eneyi E.89ORCID,Ayibanoah Theophilus9,Aworabhi-Oki Neni10,Shallcross Laura11ORCID,Molnar Andreea12,Wiseman Sue1,Hayward Andrew13,Soriano Delphine1,Birjovanu Georgiana1,Lefevre Carmen14,Olufemi Olajumoke3,Kostkova Patty1

Affiliation:

1. UCL IRDR Centre for Digital Public Health in Emergencies, University College London , London, UK

2. Department of Sociology, University of Lagos , Lagos, Nigeria

3. Department of Medical Microbiology, Lagos State University College of Medicine/Lagos State University Teaching Hospital , Lagos, Nigeria

4. Urology Unit, Department of Surgery, College of Medicine University of Lagos/Lagos University Teaching Hospital , Lagos, Nigeria

5. Neurosurgery Unit, Department of Surgery, College of Medicine University of Lagos/Lagos University Teaching Hospital , Lagos, Nigeria

6. Paediatric Surgery Unit, Department of Surgery, College of Medicine University of Lagos/Lagos University Teaching Hospital , Lagos, Nigeria

7. Department of Ophthalmology, Lagos State University Teaching Hospital , Lagos, Nigeria

8. Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine , London, UK

9. Department of Pharmacy, Niger Delta University Teaching Hospital , Bayelsa State, Nigeria

10. Department of Surgery, Niger Delta University Teaching Hospital , Bayelsa State, Nigeria

11. Institute of Health Informatics, University College London , London, UK

12. School of Software and Electrical Engineering, Swinburne University of Technology , Melbourne, Australia

13. Institute of Epidemiology and Public Health, University College London , London, UK

14. UCL Centre for Behaviour Change, University College London , London, UK

Abstract

Abstract Background In Nigeria, the prescription of surgical antibiotic prophylaxis for prevention of surgical site infection tends to be driven by local policy rather than by published guidelines (e.g. WHO and Sanford). Objectives To triangulate three datasets and understand key barriers to implementation using a behavioural science framework. Methods Surgeons (N = 94) from three teaching hospitals in Nigeria participated in an online survey and in focus group discussions about barriers to implementation. The theoretical domains framework (TDF) was used to structure question items and interview schedules. A subgroup (N = 20) piloted a gamified decision support app over the course of 6 months and reported barriers at the point of care. Results Knowledge of guidelines and intention to implement them in practice was high. Key barriers to implementation were related to environmental context and resources and concern over potential consequences of implementing recommendations within the Nigerian context applicable for similar settings in low-to-middle-income countries. Conclusions The environmental context and limited resource setting of Nigerian hospitals currently presents a significant barrier to implementation of WHO and Sanford guidelines. Research and data collected from the local context must directly inform the writing of future international guidelines to increase rates of implementation.

Funder

Economic Social Research Council

ESRC

Publisher

Oxford University Press (OUP)

Subject

General Medicine

Reference28 articles.

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3. Federal Ministries of Agriculture, Environment and Health;Antimicrobial Use and Resistance in Nigeria: Situation Analysis and Recommendations,2017

4. Antimicrobial resistance in West Africa: a systematic review and meta-analysis;Bernabé;Int J Antimicrob,2017

5. Audit of use of antimicrobial agents at a tertiary health centre in Lagos, Nigeria;Ogundele;J Public Health Epidemiol,2015

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