1. Sunnybrook Research Institute , Toronto , Canada
2. Department of Critical Care, Sunnybrook Health Sciences Centre , Toronto , Canada
3. Division of Infectious Diseases, Monash Health , Clayton, VIC , Australia
4. Division of Infectious Diseases, Public Health Ontario, Sunnybrook Health Sciences Centre, ICES, Institute of Health Policy Management and Evaluation, University of Toronto , 2075 Bayview Ave, G-wing Room 106, Toronto, ON M4N 3M5 , Canada