Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A-Reference-Cited by-同舟云学术

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Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A

Published:2018-05-04 Issue:11 Volume:46 Page:5861-5874
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Fislage Marcus¹,Zhang Jingji¹²,Brown Zuben Patrick¹,Mandava Chandra Sekhar²,Sanyal Suparna²^ORCID,Ehrenberg Måns²,Frank Joachim¹³^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA

2. Department of Cell and Molecular Biology, Uppsala University, Uppsala 75124, Sweden

3. Department of Biological Sciences, Columbia University, New York, NY, USA

Funder

National Institutes of Health

Swedish Research Council

Knut and Alice Wallenberg Foundation

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/46/11/5861/25067172/gky346.pdf

Reference60 articles.

1. Ribosomes are optimized for autocatalytic production;Reuveni;Nature,2017

2. Structural basis of the translational elongation cycle;Voorhees;Annu. Rev. Biochem.,2013

3. The busiest of all ribosomal assistants: elongation factor Tu;Kavaliauskas;Biochemistry,2012

4. Recognition of cognate transfer RNA by the 30S ribosomal subunit;Ogle;Science,2001

5. Selection of tRNA by the ribosome requires a transition from an open to a closed form;Ogle;Cell,2002

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