Xanthine Oxidase Inhibition by Febuxostat in Macrophages Suppresses Angiotensin II-Induced Aortic Fibrosis

Author:

Kondo Masateru12,Imanishi Masaki1ORCID,Fukushima Keijo3,Ikuto Raiki2,Murai Yoichi2,Horinouchi Yuya4,Izawa-Ishizawa Yuki4,Goda Mitsuhiro1,Zamami Yoshito12,Takechi Kenshi5,Chuma Masayuki5,Ikeda Yasumasa4,Fujino Hiromichi3,Tsuchiya Koichiro6,Ishizawa Keisuke12

Affiliation:

1. Department of Pharmacy, Tokushima University Hospital, Tokushima, Japan

2. Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan

3. Department of Pharmacology for Life Sciences, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan

4. Department of Pharmacology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan

5. Clinical Trial Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima, Japan

6. Department of Medical Pharmacology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan

Funder

JSPS KAKENHI

Japan Heart Foundation

Takeda Science Foundation

Publisher

Oxford University Press (OUP)

Subject

Internal Medicine

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