The growing fears of the other Successors over the burgeoning power of the Antigonid dynasty, which was impinging on their own kingdoms, led to the formation of a coalition aimed at removing the Antigonids from power. The actions of the coalition eventually culminated in the battle of Ipsus in 301 BC, which proved to be a watershed in the history of the Diadochoi. This chapter discusses the preliminaries to the battle, the location, and manoeuvring of the participants, and provides analysis concerning the merits of their strategies. Antigonus Monophthalmus was killed during the battle, and Demetrius became the sole king of the fragmented Antigonid domains.