This chapter describes how we can learn from the social movements of the 1960s in the United States and apply insights from those social movements to address social injustice today. Social movements have had, and will continue to have, a powerful impact on medicine and public health, motivating and energizing health workers to address social injustice. The authors, in part drawing from their personal experiences, describe the civil rights movement, the student movement, the anti-war movement, the women’s movement, the gay rights movement, and new social movements. The authors conclude that the experiences of the 1960s teach us that, as new social movements emerge, it is important for single-issue movements to unite with each other and collaborate for progressive change.