Humans and alcohol have shared a very long history. In this final chapter, we highlight some of the key findings that emerge from the chapters in this book, in particular the evolutionary history of our adaptation to alcohol consumption and the social role that alcohol consumption plays, and has played, in human societies across the world. This raises a major contradiction in the literature, namely the fact that, despite this long history, the medical profession typically views alcohol as destructive. We draw attention to several avenues that would repay future research and how humans’ relationship with alcohol stands to change and evolve.