This chapter outlines key methodological and ethical issues that researchers face when conducting social science and health research with forcibly displaced populations. It highlights specific considerations for researchers, using case studies from research conducted with refugees in Malaysia and asylum seekers in Israel. The Malaysian case considers patient safety, accessing hidden populations, non-maleficence, beneficence, the nuances of researcher–participant relationships, and the importance of input from local ethics committees. The Israel case describes the intricacies of working with asylum seekers in non-camp settings, benefits for participants, the threat of deportation, the risk of participant reliance on researchers for support services, working as a cultural liaison, and the potential for hostility from the government. The chapter underscores the unique challenges stemming from the complexity and diversity of these populations. Finally, it provides guidelines and recommendations for ethical review boards evaluating proposals for research with forcibly displaced populations.