A notion of rationality represents a structure that can be used to explain, evaluate, and recommend a certain course of action. Full rationality, independent of context, builds such a structure based on the rules of logic and statistical inference. Ecological rationality, on the other hand, focuses on the interaction between the human mind and the task environment. This chapter argues that ecological rationality can provide an operational framework for evolutionary medicine based on compatible foundational concepts. Risk literacy and numeracy methods developed on the basis of an adaptive toolbox approach constitute effective education tools. An evolutionary approach to medical education facilitates the integration of these accessible and well-retained educational tools for physicians and their patients, and can enrich public health policymaking.