Personalized external aortic root support

Author:

Nemec Petr1ORCID,Pepper John2,Fila Petr1ORCID

Affiliation:

1. Centre of Cardiovascular Surgery and Transplantations, Brno, Czech Republic

2. Royal Brompton Hospital, London, UK

Abstract

Abstract OBJECTIVES Implantation of a personalized external aortic root support (PEARS) can prevent dilatation of the aortic root and ascending aorta in patients with aortopathy of various aetiologies. Because PEARS is an emerging technology, all aspects concerning indications, surgical technique and safety should be elucidated. Our goal was to summarize all of these aspects so that physicians and patients would have sufficient information to evaluate this alternative approach. METHODS Between April 2004 and March 2020, 317 patients underwent PEARS operations at 25 surgical centres in 9 countries. RESULTS The most common indication was Marfan syndrome (57%). The single perioperative death represented a mortality of 0.3%. The long-term experience comprises 871 patient/years with 1 patient living for 15 years and 19 patients living for more than 10 years. CONCLUSIONS PEARS seems to be a promising method of treatment of dilatation of the aortic root and/or ascending aorta. Multicentre observational studies are needed to gain more experience because this operation is still uncommon and the number of operations per surgeon/centre is low.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Pulmonary and Respiratory Medicine,Surgery

Reference24 articles.

1. 2017 ESC/EACTS Guidelines for the management of valvular heart disease;Falk;Eur J Cardiothorac Surg 2017;52:616–64

2. Valve-sparing aortic root replacement (David I procedure) in Marfan disease: single-centre 20-year experience in more than 100 patients;Martens;Eur J Cardiothorac Surg,2019

3. The Tailor of Gloucester: a jacket for the Marfan’s aorta;Golesworthy;Lancet,2004

4. External aortic root support to prevent aortic dilatation in patients with Marfan syndrome;Izgi;J Am Coll Cardiol,2018

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