The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets
Author:
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/41/2/978/16801170/gks1078.pdf
Reference40 articles.
1. Gene silencing by microRNAs: contributions of translational repression and mRNA decay;Huntzinger;Nat. Rev. Genet.,2011
2. The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC;Fabian;Nat. Struct. Mol. Biol.,2012
3. Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation;Fabian;Mol. Cell,2009
4. The silencing domain of GW182 interacts with PABP to promote translational repression and degradation of miRNA targets and is required for target release;Zekri;Mol. Cell. Biol.,2009
5. Two PABP-binding sites in GW182 proteins promote miRNA-mediated gene silencing;Huntzinger;EMBO J.,2010
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