Green Analytical Toxicology for the Determination of Cocaine Metabolites-Reference-Cited by-同舟云学术

Green Analytical Toxicology for the Determination of Cocaine Metabolites

Published:2022-01-12 Issue:9 Volume:46 Page:965-978
ISSN:0146-4760
Container-title:Journal of Analytical Toxicology
language:en
Short-container-title:

Author:

de Paula Meirelles Gabriela¹,Fabris André Luis¹^ORCID,Ferreira dos Santos Karina¹,Costa José Luiz²³^ORCID,Yonamine Mauricio¹

Affiliation:

1. Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of Sao Paulo (USP) , Av. Professor Lineu Prestes, 580, 13B, Sao Paulo, SP 05508-000, Brazil

2. Campinas Poison Control Center, University of Campinas (UNICAMP) , R. Tessália Vieira de Camargo, 126, Campinas, SP 13083-859, Brazil

3. Faculty of Pharmaceutical Sciences, University of Campinas (UNICAMP) , R. Cândido Portinari, 200, Campinas, SP 13083-871, Brazil

Abstract

Abstract Brazil is the third largest contributor to Green Analytical Chemistry, and there is significant participation of toxicologists in the development and improvement of environmental techniques. Currently, toxicologists have their own strategies and guidelines to promote the reduction/replacement or elimination of solvents, reduce the impacts of derivatization and save time, among other objectives, due to the peculiarities of toxicological analysis. Thus, this review aims to propose the concept of Green Analytical Toxicology and conduct a discussion about its relevance and applications specifically in forensic toxicology, using the microextraction methods developed for the determination of cocaine and its metabolites as examples.

Publisher

Oxford University Press (OUP)

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Toxicology,Environmental Chemistry,Analytical Chemistry

Link

https://academic.oup.com/jat/advance-article-pdf/doi/10.1093/jat/bkac005/42594944/bkac005.pdf

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