Improvements in Hypertension Control in the Rural Longitudinal HAALSI Cohort of South African Adults Aged 40 and Older, From 2014 to 2019

Author:

Abrahams-Gessel Shafika1ORCID,Gómez-Olivé F Xavier234,Tollman Stephen345,Wade Alisha N34,Du Toit Jacques D3,Ferro Enrico G67,Kabudula Chodziwadziwa W34,Gaziano Thomas A128

Affiliation:

1. Center for Health Decision Science, Harvard T.H. Chan School of Public Health , Boston, Massachusetts , USA

2. Harvard Center for Population and Development Studies, Harvard University , Cambridge, Massachusetts , USA

3. Medical Research Council/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), University of the Witwatersrand , Johannesburg , South Africa

4. Africa Wits-INDEPTH Partnership for Genomic Studies, University of the Witwatersrand , Johannesburg , South Africa

5. Department of Epidemiology and Global Health, Umeå University , Umeå , Sweden

6. Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center , Boston, Massachusetts , USA

7. Harvard Medical School , Boston, Massachusetts , USA

8. Cardiovascular Medicine Division, Brigham & Women’s Hospital , Boston, Massachusetts , USA

Abstract

Abstract Background Over half of the South African adults aged 45 years and older have hypertension but its effective management along the treatment cascade (awareness, treatment, and control) remains poorly understood. Methods We compared the prevalence of all stages of the hypertension treatment cascade in the rural HAALSI cohort of older adults at baseline and after four years of follow-up using household surveys and blood pressure data. Hypertension was a mean systolic blood pressure >140 mm Hg or diastolic pressure >90 mm Hg, or current use of anti-hypertension medication. Control was a mean blood pressure <140/90 mm Hg. The effects of sex and age on the treatment cascade at follow-up were assessed. Multivariate Poisson regression models were used to estimate prevalence ratios along the treatment cascade at follow-up. Results Prevalence along the treatment cascade increased from baseline (B) to follow-up (F): awareness (64.4% vs. 83.6%), treatment (49.7% vs. 73.9%), and control (22.8% vs. 41.3%). At both time points, women had higher levels of awareness (B: 70.5% vs. 56.3%; F: 88.1% vs. 76.7%), treatment (B: 55.9% vs. 41.55; F: 79.9% vs. 64.7%), and control (B: 26.5% vs. 17.9%; F: 44.8% vs. 35.7%). Prevalence along the cascade increased linearly with age for everyone. Predictors of awareness included being female, elderly, or visiting a primary health clinic three times in the previous 3 months, and the latter two also predicted hypertension control. Conclusions There were significant improvements in awareness, treatment, and control of hypertension from baseline to follow-up and women fared better at all stages, at both time points.

Funder

National Institute on Aging

Department of Science and Innovation, South Africa

Medical Research Council

Wellcome Trust

Harvard T.H. Chan School of Public Health

MRC/Wits Rural Public Health and Health Transitions Research Unit

NIH

AWI-Gen Collaborative Centre

Fogarty International Center

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Internal Medicine

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