Papular acantholytic dermatosis: a rare cause of genital rash

Abstract

A 52-year-old woman presented to our hospital’s STD unit with multiple asymptomatic skin-coloured papules along both inguinal folds. The patient noted the onset of these lesions approximately 2 months before her presentation. A punch biopsy was performed, which revealed hyperkeratosis and hypergranulosis in the epidermis along with acantholytic and dyskeratotic foci, leading to the diagnosis of papular acantholytic dermatosis. Our patient showed a remarkable response after topical corticosteroid use followed by topical calcineurin inhibitor use.