Bony side-effects in acitretin treatment: is monitoring required?

Abstract

Acitretin is an oral retinoid and the active metabolite of etidronate. While most commonly used for the treatment of inflammatory disorders, its indications extend to disorders of keratinization in the paediatric population. In the midst of a safety announcement on the side-effects of isotretinoin by the UK Commission on Human Medicines, a debate on whether acitretin monitoring should also be updated is encouraged.