Potential correlation between anti-laminin 332 autoantibodies and malignant tumours in anti-BP180-type mucous membrane pemphigoid

Author:

Li Xiaoguang1,Pas Hendri H2,Qian Hua1,Rashid Hanan2,Horvath Barbara2,Yilmaz Kaan34,van Beek Nina3,Schmidt Enno35ORCID,Zillikens Detlef3,Ishii Norito6,Tsuruta Daisuke7,Hashimoto Takashi7

Affiliation:

1. School of Public Health and Laboratory Medicine, Hunan University of Medicine , Huaihua , China

2. Center for Blistering Diseases, Department of Dermatology, University Medical Center Groningen, University of Groningen , Groningen , the Netherlands

3. Department of Dermatology, University of Lübeck , Lübeck , Germany

4. Department of Dermatology, University of Heidelberg, Medical Faculty Mannheim , Mannheim , Germany

5. Lübeck Institute of Experimental Dermatology, University of Lübeck , Lübeck , Germany

6. Department of Dermatology, Kurume University School of Medicine , Kurume , Japan

7. Department of Dermatology, Graduate School of Medicine, Osaka Metropolitan University , Osaka , Japan

Abstract

To the best of our knowledge, this is the first large cohort study to analyse the potential correlations between anti-laminin (LM) 332 autoantibodies and malignant tumours in 520 patients with anti-BP180-type mucous membrane pemphigoid (BP180-MMP) recruited from four countries in two continents. Patients who were anti-LM332 autoantibody (–) with BP180-MMP were used as a control group. The results in this study support that anti-LM332 autoantibodies are positively correlated with malignant tumours in people with BP180-MMP, particularly in Europe.

Funder

JSPS KAKENHI

Publisher

Oxford University Press (OUP)

Reference5 articles.

1. Clinical and immunological findings in 55 patients with anti-laminin 332-type mucous membrane pemphigoid;Li;Br J Dermatol,2021

2. A sensitive and specific assay for the serological diagnosis of antilaminin 332 mucous membrane pemphigoid;Goletz;Br J Dermatol,2019

3. Clinical and immunological studies of 332 Japanese patients tentatively diagnosed as anti-BP180-type mucous membrane pemphigoid: a novel BP180 C-terminal domain enzyme-linked immunosorbent assay;Yasukochi;Acta Derm Venereol,2016

4. comparison of two diagnostic assays for anti-laminin 332 mucous membrane pemphigoid;Goletz;Front Immunol,2021

5. Anti-laminin 332-type mucous membrane pemphigoid;Shi;Biomolecules,2022

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3