Successful treatment of cutaneous-onset Erdheim–Chester disease with cobimetinib and anakinra-Reference-Cited by-同舟云学术

Successful treatment of cutaneous-onset Erdheim–Chester disease with cobimetinib and anakinra

Published:2024-01-17 Issue:5 Volume:49 Page:523-525
ISSN:0307-6938
Container-title:Clinical and Experimental Dermatology
language:en
Short-container-title:

Author:

Aromolo Italo Francesco¹^ORCID,Moltrasio Chiara²³,Maronese Carlo Alberto¹^ORCID,Campochiaro Corrado⁴^ORCID,Bonometti Arturo⁵,Berti Emilio¹,Passoni Emanuela²,Marzano Angelo¹²

Affiliation:

1. Department of Pathophysiology and Transplantation, University of Milan , Milan , Italy

2. Dermatology Unit, IRCCS Foundation Maggiore Policlinico Hospital , Lombardia, Milan , Italy

3. Department of Medical Surgical and Health Sciences, University of Trieste , Trieste, Friuli-Venezia Giulia , Italy

4. San Raffaele Hospital , Milan , Italy

5. Pathology Unit, Humanitas University , Rozzano, Milan , Italy

Abstract

Erdheim–Chester disease is a rare multisystem non-Langerhans cell histiocytosis. We report the case of a patient with BRAF wildtype Erdheim–Chester disease presenting with facial nodular xanthomas and developing systemic involvement 10 years later. The patient was successfully treated with a combination of anakinra and cobimetinib.

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/ced/advance-article-pdf/doi/10.1093/ced/llae014/56826874/llae014.pdf

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