A retrospective review of pregnancies in our psoriasis biologic cohort

Author:

Wolfe Charlotte1ORCID,Kennard Benjamin1,Bewley Anthony1,Mehrtens Sarah1

Affiliation:

1. Department of Dermatology, Barts Health NHS Trust , London , UK

Abstract

This review assesses the real-world pregnancy outcomes of 15 pregnancies occurring while on biologic therapy in our psoriasis cohort over a 10-year period. Of the 15 pregnancies, there were 9 successful pregnancies, 4 first trimester miscarriages, 1 stillbirth at 28 weeks and 1 termination of pregnancy. Our study shows that the majority of pregnancies were successful; this reinforces previously published data that biologic therapy for psoriasis in pregnancy does not carry additional significant clinical risk, and contributes to the body of evidence supporting the safety of biologic therapy in pregnancy.

Publisher

Oxford University Press (OUP)

Reference5 articles.

1. The impact of biologics on the quality of life of psoriasis patients and the economics of psoriasis care;Stein;Semin Cutan Med Surg,2005

2. British Association of Dermatologists guidelines for biologic therapy for psoriasis 2017;Smith;Br J Dermatol,2017

3. Benefits and risks of IgG transplacental transfer;Ciobanu;Diagnostics (Basel),2020

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