Risk factors for the development of Stevens–Johnson syndrome/toxic epidermal necrolysis following drug administration: a systematic review and meta-analysis-Reference-Cited by-同舟云学术

Risk factors for the development of Stevens–Johnson syndrome/toxic epidermal necrolysis following drug administration: a systematic review and meta-analysis

Published:2024-05-15 Issue: Volume: Page:
ISSN:0307-6938
Container-title:Clinical and Experimental Dermatology
language:en
Short-container-title:

Author:

Fathima Samaah¹,Grainge Matthew J²,Wainman Hannah³⁴^ORCID,Swiderski Mikolaj⁵,Gran Sonia⁵

Affiliation:

1. School of Medicine, University of Nottingham , Nottingham , UK

2. Lifespan and Population Health, School of Medicine, University of Nottingham , UK

3. Dermatology Department, Bristol Royal Infirmary , Bristol , UK

4. Bristol Medical School, University of Bristol , Bristol , UK

5. Centre of Evidence Based Dermatology, School of Medicine, University of Nottingham , Nottingham , UK

Abstract

The aim of this systematic review was to determine risk factors for the development of Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) following drug administration. The study protocol was registered on PROSPERO. The PRISMA guidelines were followed. On 17 October 2022, a search, advised by a librarian, was conducted in MEDLINE and Embase. Five studies were pooled. We report that HIV and male gender may be risk factors for SJS/TEN; however, this review was limited by a low number and quality of included studies. We conclude that a well-designed, large population-based case–control study with an appropriate control group is required to assess risk factors for the development of drug-induced SJS/TEN.

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/ced/advance-article-pdf/doi/10.1093/ced/llae183/58998993/llae183.pdf

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4. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.;Page;BMJ (Clinical research ed.),2021