A male infant with ALK-positive histiocytosis recovered spontaneously-Reference-Cited by-同舟云学术

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A male infant with ALK-positive histiocytosis recovered spontaneously

Published:2024-01-18 Issue:6 Volume:49 Page:620-622
ISSN:0307-6938
Container-title:Clinical and Experimental Dermatology
language:en
Short-container-title:

Author:

Xu Zhijun¹^ORCID,Huang Lining²,Xue Ruzeng²

Affiliation:

1. Department of Dermatology, Shenshan Medical Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University , Shanwei , China

2. Department of Dermatology, Dermatology Hospital, Southern Medical University , Guangzhou , China

Abstract

Anaplastic lymphoma kinase (ALK)-positive histiocytosis is a rare subtype of histiocytic neoplasm characterized by expression of ALK. We present a case of a male infant with ALK-positive histiocytosis, confirmed by pathological analysis and detection of ALK using fluorescence in situ hybridization. The boy recovered spontaneously and all the lesions completely disappeared without special treatment.

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/ced/advance-article-pdf/doi/10.1093/ced/llae022/56994365/llae022.pdf

Reference4 articles.

1. ALK+ histiocytosis: a novel type of systemic histiocytic proliferative disorder of early infancy;Chan;Blood,2008

2. Expanding the phenotype of ALK-positive histiocytosis: a report of 2 cases;Huang;Pediatr Dev Pathol,2018

3. ALK-positive histiocytosis: an expanded clinicopathologic spectrum and frequent presence of KIF5B-ALK fusion;Chang;Mod Pathol,2019

4. ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition;Kemps;Blood,2022

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