Alcohol septal ablation for hypertrophic obstructive cardiomyopathy and bilateral lung transplantation for idiopathic pulmonary fibrosis: a case report

Author:

Puchnerova Veronika1ORCID,Bonaventura Jiri1ORCID,Lischke Robert2ORCID,Veselka Josef1

Affiliation:

1. Department of Cardiology, Second Faculty of Medicine, Charles University and Motol University Hospital , V Uvalu 84/1, 150 06 Prague , Czech Republic

2. Prague Lung Transplant Program, Third Department of Surgery, First Faculty of Medicine, Charles University and Motol University Hospital , Prague , Czech Republic

Abstract

Abstract Background We present an uncommon case of a patient with hypertrophic obstructive cardiomyopathy and idiopathic pulmonary fibrosis. The case demonstrates the importance of pre-transplant cardiology workup and the need of interdisciplinary approach in diagnosing the cause of dyspnoea. Case summary The 52-year-old male patient was diagnosed with idiopathic pulmonary fibrosis in 2019 and gradually became oxygen dependent due to progression of dyspnoea. Bilateral lung transplantation was recommended in 2021. During pre-transplant cardiology workup, the patient was diagnosed with hypertrophic cardiomyopathy with left ventricular outflow tract (LVOT) obstruction. Considering the high surgical risk of the patient, alcohol septal ablation was performed with subsequent decrease of LVOT gradient. Bilateral lung transplantation was successfully performed afterwards. The patient’s symptoms improved to NYHA class II at one year follow-up. Discussion We present a rare case of combined cause of dyspnoea—coexistence of hypertrophic obstructive cardiomyopathy and idiopathic pulmonary fibrosis in one patient. Due to high surgical risk, the patient underwent alcohol septal ablation with successful elimination of LVOT gradient and subsequently bilateral lung transplantation.

Funder

Ministry of Health, Czech Republic

University Hospital Motol, Prague, Czech Republic

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

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1. Nintedanib/pirfenidone;Reactions Weekly;2024-04-06

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