1. Department of Cardiology, Royal Free Hospital, Pond Street, Hampstead, London, NW3 2QG, UK
2. Barts Heart Centre, St. Bartholomew’s Hospital, West Smithfield, London EC1A 7BE, UK
3. Institute of Cardiovascular Science, University College London, 62 Huntley Street, Fitzrovia, London WC1E 6DD, UK