Multisystem inflammatory syndrome in adults with cardiac engagement: a case report and literature review

Author:

Massoud Linda1ORCID,Westling Katarina23,Fischer Marie4,Najjar Emil15

Affiliation:

1. Heart and Vascular Theme, Karolinska University Hospital , Eugeniavägen 3, Solna, 171 76 Stockholm , Sweden

2. Department of Infectious Disease, Karolinska University Hospital , Stockholm , Sweden

3. Department of Medicine, Division of Infectious diseases and Dermatology, Karolinska Institute , Stockholm , Sweden

4. Department of Rheumatology, Karolinska University Hospital , Stockholm , Sweden

5. Department of Medicine, Karolinska Institute , Stockholm , Sweden

Abstract

Abstract Background Following infection with severe acute respiratory syndrome coronavirus, a post-infectious multisystem inflammatory syndrome in adults (MIS-A) has been identified. It affects multiple organ systems and can lead to multi-organic failure. Case summary This case report describes a patient with MIS-A with significant cardiac involvement including peri-myocarditis, pulmonary hypertension, right-sided heart failure, tricuspid regurgitation, and cardiogenic shock. After being diagnosed and treated correctly for MIS-A, the patient recovered completely, without any cardiac sequelae. Discussion The hyperinflammation in MIS-A can have cardiac engagement. Although more research is required to further clarify the underlying mechanisms, prompt diagnosis and anti-inflammatory treatment are crucial for better outcomes and cardiac recovery.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

Reference12 articles.

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