Morphological components detection for super-depth-of-field bio-micrograph based on deep learning

Author:

Du XiaohuiORCID,Wang Xiangzhou,Xu Fan,Zhang Jing,Huo Yibo,Ni Guangmin,Hao Ruqian,Liu Juanxiu,Liu Lin

Abstract

Abstract Accompanied with the clinical routine examination demand increase sharply, the efficiency and accuracy are the first priority. However, automatic classification and localization of cells in microscopic images in super depth of Field (SDoF) system remains great challenges. In this paper, we advance an object detection algorithm for cells in the SDoF micrograph based on Retinanet model. Compared with the current mainstream algorithm, the mean average precision (mAP) index is significantly improved. In the experiment of leucorrhea samples and fecal samples, mAP indexes are 83.1% and 88.1%, respectively, with an average increase of 10%. The object detection model proposed in this paper can be applied to feces and leucorrhea detection equipment, and significantly improve the detection efficiency and accuracy.

Funder

Fundamental Research Funds for the Central Universities

Chengdu Science and Technology Bureau focuses on research and development support plan

National Natural Science Foundation of China

Publisher

Oxford University Press (OUP)

Subject

Radiology, Nuclear Medicine and imaging,Instrumentation,Structural Biology

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