Effects of the sodium–glucose co-transporter 2 inhibitor dapagliflozin in patients with type 2 diabetes and Stages 3b–4 chronic kidney disease

Author:

Dekkers Claire C J1,Wheeler David C2,Sjöström C David3,Stefansson Bergur V3,Cain Valerie4,Heerspink Hiddo J L1

Affiliation:

1. Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

2. Centre for Nephrology, University College London, London, UK

3. Department of Cardiovascular and metabolic diseases, Global Medicines Development, AstraZeneca, Gothenburg, Sweden

4. Department of Biometrics and Information Sciences, Bogier Clinical and IT Solutions, Raleigh, NC, USA

Funder

AstraZeneca

Publisher

Oxford University Press (OUP)

Subject

Transplantation,Nephrology

Reference31 articles.

1. Chronic kidney disease in US adults with type 2 diabetes: an updated national estimate of prevalence based on Kidney Disease: Improving Global Outcomes (KDIGO) staging;Bailey;BMC Res Notes,2014

2. Kidney disease and increased mortality risk in type 2 diabetes;Afkarian;J Am Soc Nephrol,2013

3. Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications;Heerspink;Circulation,2016

4. Dapagliflozin reduces albuminuria in patients with diabetes and hypertension receiving renin–angiotensin blockers;Heerspink;Diabetes Obes Metab,2016

5. Empagliflozin and progression of kidney disease in type 2 diabetes;Wanner;N Engl J Med,2016

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