Transcription yield of fully 2′-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants
Author:
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/43/15/7480/17434623/gkv734.pdf
Reference42 articles.
1. Building oligonucleotide therapeutics using non-natural chemistries
2. Advantages of 2'-O-methyl oligoribonucleotide probes for detecting RNA targets
3. In vivo activity of nuclease-resistant siRNAs
4. Small interfering RNAs containing full 2′-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity
5. Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing
Cited by 53 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Synthesis, Reverse Transcription, Replication, and Inter-Transcription of 2′-Modified Nucleic Acids with Evolved Thermophilic Polymerases: Efforts toward Multidimensional Expansion of the Central Dogma;ACS Synthetic Biology;2023-08-30
2. Modified Nucleotides for Chemical and Enzymatic Synthesis of Therapeutic RNA;Current Medicinal Chemistry;2023-04
3. CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids;Nucleic Acids Research;2023-01-06
4. N6-methyladenosine (m6A) RNA modification as a metabolic switch between plant cell survival and death in leaf senescence;Frontiers in Plant Science;2023-01-04
5. A two-residue nascent-strand steric gate controls synthesis of 2′-O-methyl- and 2′-O-(2-methoxyethyl)-RNA;Nature Chemistry;2022-10-13
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3