The effect of autocrine motility factor alone and in combination with methyl jasmonate on liver cancer cell growth-Reference-Cited by-同舟云学术

The effect of autocrine motility factor alone and in combination with methyl jasmonate on liver cancer cell growth

Published:2021-05-14 Issue:7 Volume:85 Page:1711-1715
ISSN:1347-6947
Container-title:Bioscience, Biotechnology, and Biochemistry
language:en
Short-container-title:

Author:

Jeoung Nam Ho¹,Jo Ae Lim¹,Park Hee Sung²

Affiliation:

1. Department of Pharmaceutical Engineering, Catholic University of Daegu, Gyeongsan, Korea

2. Department of Biomedical Science, Catholic University of Daegu, Gyeongsan, Korea

Abstract

ABSTRACT Neoplastic cells secrete autocrine motility factor (AMF) to stimulate the motility of cancer cells. In this study, AMF secreted from HT-29 colorectal cancer cells selectively suppressed liver cancer cells by downregulating pAKT and β-catenin. In addition, HT-29 AMF significantly augmented the activity of methyl jasmonate against liver cancer cells and is a promising alternative for liver cancer therapy.

Funder

Daegu Catholic University

Publisher

Oxford University Press (OUP)

Subject

Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology

Link

http://academic.oup.com/bbb/advance-article-pdf/doi/10.1093/bbb/zbab087/38488398/zbab087.pdf

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